?SPECTRAL STUDIES OF BINARY AND TERNARY COMPLEXES OF SOME SULFA-DRUGS

Authors

  • Nadia A Abdalla Chemistry Department, Faculty of Science, Aswan, Egypt
  • A H Amrailah Chemistry Department, Faculty of Science, Aswan, Egypt
  • M A Chandour Chemistry Department, Faculty of Science, Aswan, Egypt
  • E A Kasim Chemistry Department, Faculty of Science, Aswan, Egypt
  • 0 A Farghali Chemistry Department, Faculty of Science, Aswan, Egypt

Keywords:

Binary and ternary complexes, Sulfadrugs, Sulfamethazine, Sulfathiazole, Tolbutamide.

Abstract

The complexes of Sulfamethazine(SMZ),Sulfathiazole(STZ)andTolbutamide(TA)withCum) andFe(III)havebeen
investigated. The formation of I:I and 1:2species were inferred from electronic spectra and conductivity measure-
ments. The bonding sites are the oxygen of sulphonamide group and heterocyclic nitrogen atom of aryl moiety.
Interaction of Cu(lI) and Fe(III) ions with salysaldehyde as the primary ligand and with SMZ, STZ and TA as
secondary ligands hasbeenstudied spectrophotometrically.The dataindicatethe formationofternarycomplexes with
stoichiometric ratio of (1:I:I). Stabilityofbinary andternary complexeswas foundtobe intheorder. SMZ>STZ>TA

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Published

2001-06-18

How to Cite

Abdalla, N. A., Amrailah, A. H., Chandour, M. A., Kasim, E. A., & Farghali, 0 A. (2001). ?SPECTRAL STUDIES OF BINARY AND TERNARY COMPLEXES OF SOME SULFA-DRUGS. Biological Sciences - PJSIR, 44(3), 148–152. Retrieved from http://biostaging.pjsir.org/index.php/biological-sciences/article/view/1900

Issue

Vol. 44 No. 3 (2001): Pakistan Journal of Scientific and Industrial Research

Section

Articles