?URINARY EXCRETION OF CHLOROQUINE AND ITS METABOLITES

Authors

  • CO Usifohs Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
  • SA Adelusi Department of Pharmaceutical Chemistry, Faculty of Pharmacy, University of Benin, Benin City, Nigeria
  • IO Ogunleye Department of Biochemistry, Ondo State University, Ado-Ekiti, Nigeria

Keywords:

Chloroquine and its metabolites, Urinary excretion, Albino rats.

Abstract

The amount of individual metabolites of chloroquine present in the urine of Wistar Albino rats was determined. The
desethylchloroquine and the 4 -amino -7 -chloroquinoline were identified in this study similar to those'obtained in man by
previous investigations. The results of the investigation suggest that rat metabolises chloroquine in a similar way as'man.

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Published

2000-06-26

How to Cite

Usifohs, C., Adelusi, S., & Ogunleye, I. (2000). ?URINARY EXCRETION OF CHLOROQUINE AND ITS METABOLITES. Biological Sciences - PJSIR, 43(4), 205–207. Retrieved from http://biostaging.pjsir.org/index.php/biological-sciences/article/view/2033

Issue

Vol. 43 No. 4 (2000): Pakistan Journal of Scientific and Industrial Research

Section

Articles